This bears out my (admittedly limited) experiences with blue agave -- it made for a moister, denser muffin than using sugar, but my body reacted to it exactly the same.

Since I've cut out sodas and whatnot from my diet, and cook most of my own meals, I don't worry too much HFCS as a rule, but it would have been nice if this really were kinder to my blood sugar levels.